Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice
نویسندگان
چکیده
منابع مشابه
LIVER Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2
Background: Angiotensin converting enzyme (ACE) 2 is a recently identified homologue of ACE that may counterregulate the actions of angiotensin (Ang) II by facilitating its breakdown to Ang 1–7. The reninangiotensin system (RAS) has been implicated in the pathogenesis of cirrhosis but the role of ACE2 in liver disease is not known. Aims: This study examined the effects of liver injury on ACE2 e...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2009
ISSN: 0270-9139
DOI: 10.1002/hep.23104